How and where to order Premarin (Estrogens Conjugated) 0.625 mg tablets online:

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Forms: Conjugated Estrogens (Premarin) 0.625 mg tablets
Quantity: 14-336 pills
Type: Estrogens Conjugated brand, Premarin generic
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Indications and usage:

Premarin is a mixture of estrogens indicated for:

  • Treatment of moderate to severe vasomotor symptoms due to menopause.
  • Treatment of moderate to severe vulvar and vaginal atrophy due to menopause.
  • Treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure.
  • Treatment of breast cancer (for palliation only) in appropriately selected women and men with metastatic disease.
  • Treatment of advanced androgen-dependent carcinoma of the prostate (for palliation only).
  • Prevention of postmenopausal osteoporosis.


    Dosage and administration:

  • Daily administration of 0.3, 0.45, 0.625, 0.9, and 1.25 mg.
  • Cyclic administration of 0.3, 0.625, and 1.25 mg.


    Overdosage:

    Overdosage of estrogen may cause nausea, vomiting, breast tenderness, abdominal pain, drowsiness and fatigue, and withdrawal bleeding may occur in women. Treatment of overdose consists of discontinuation of Premarin therapy with institution of appropriate symptomatic care.


    Dosage forms and strengths:

    Premarin (Conjugated Estrogens) tablets: 0.3, 0.45, 0.625, 0.9, and 1.25 mg.


    Contraindications:

  • Undiagnosed abnormal genital bleeding.
  • Known, suspected, or history of breast cancer except in appropriately selected patients being treated for metastatic diseases.
  • Known or suspected estrogen-dependent neoplasia.
  • Active DVT, PE, or a history of these conditions.
  • Active arterial thromboembolic disease (for example, stroke and MI), or a history of these conditions.
  • Known anaphylactic reaction or angioedema with Premarin.
  • Known liver impairment or disease.
  • Known protein C, protein S, or antithrombin deficiency, or other known thrombophilic disorders.
  • Known or suspected pregnancy.


    Warnings and precautions:

  • Estrogens increase the risk of gallbladder disease.
  • Discontinue estrogen if severe hypercalcemia, loss of vision, severe hypertriglyceridemia or cholestatic jaundice occurs.
  • Monitor thyroid function in women on thyroid replacement therapy.


    Adverse reactions, side effects:

    Most common adverse reactions ( >= 5 percent) are: abdominal pain, asthenia, pain, back pain, headache, flatulence, depression, nausea, insomnia, breast pain, leucorrhea, endometrial hyperplasia, vaginal hemorrhage, and vaginitis.

    To report suspected adverse reactions, contact Pfizer Inc. or your local FDA.


    Drug interactions:

    Inducers and/or inhibitors of CYP3A4 may affect estrogen drug metabolism.

    Related medications:

    Arimidex (Anastrozole) 1 mg tablets


    Use in specific populations:

    Nursing mothers

    Estrogen administration has been shown to decrease the quantity and quality of breast milk.

    Geriatric use

    An increased risk of probable dementia in women over 65 years of age was reported in the Women's Health Initiative Memory ancillary studies of the Women's Health Initiative.


    Patient counseling information:

    Vaginal bleeding

    Inform postmenopausal women of the importance of reporting vaginal bleeding to their healthcare provider as soon as possible.

    Possible serious adverse reactions with estrogens

    Inform postmenopausal women of possible serious adverse reactions of estrogen therapy including cardiovascular disorders, malignant neoplasms, and probable dementia.

    Possible less serious but common adverse reactions with estrogens

    Inform postmenopausal women of possible less serious but common adverse reactions of estrogen therapy such as headache, breast pain and tenderness, nausea and vomiting.


    Here is a list of popular medications containing conjugated estrogens as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Conjugase
  • Tablets, Sugar-Coated; Oral; Estrogens Conjugated 0.625 mg
    		•
  • Elder Pharmaceuticals
    		•
    Premarin
  • Cream; Topical, Vaginal; Estrogens Conjugated 0.0625%
  • Injectable; Injection; Estrogens Conjugated 25 mg
  • Tablets; Oral; Estrogens Conjugated 0.3 mg
  • Tablets; Oral; Estrogens Conjugated 0.45 mg
  • Tablets; Oral; Estrogens Conjugated 0.625 mg
  • Tablets; Oral; Estrogens Conjugated 0.9 mg
  • Tablets; Oral; Estrogens Conjugated 1.25 mg
  • Tablets; Oral; Estrogens Conjugated 2.5 mg
    		•
  • Pfizer
  • IDS Group
  • Institute of Pharmaceutical Research and Technology
  • Metro Drug Distribution
  • Wyeth
  • Zuellig Pharma
    		•
    Presomen 28
  • Tablets, Coated; Oral; Estrogens Conjugated 0.3 mg
  • Tablets, Coated; Oral; Estrogens Conjugated 0.6 mg
  • Tablets, Coated; Oral; Estrogens Conjugated 1.25 mg
    		•
  • Pfizer
  • Solvay
  • Wyeth
    		•